Title: Top 10 Hotels in Rios Blanco y Negro Wildlife Reserve from $42 - Competitive Prices | Expedia.com [Rios Blanco y Negro Wildlife Reserve Travel Guide](https://expedia.com/Rios-Blanco-Y-Negro-Wildlife-Reserve.dx6350258)[Vacation Rentals in Rios Blanco y Negro Wildlife Reserve](https://expedia.com/Rios-Blanco-Y-Negro-Wildlife-Reserve-Vacation-Rentals.d6350258.Travel-Guide-VacationRentals)[Flights to Rios Blanco y Negro Wildlife Reserve](https://expedia.com/Cheap-Flights-To-Rios-Blanco-Y-Negro-Wildlife-Reserve.d6350258.Travel-Guide-Flights)[Car Rentals in Rios Blanco y Negro Wildlife Reserve](https://expedia.com/Car-Rentals-In-Rios-Blanco-Y-Negro-Wildlife-Reserve.d6350258.Car-Rental-Guide)[Rios Blanco y Negro Wildlife Reserve Vacation Packages](https://expedia.com/Rios-Blanco-Y-Negro-Wildlife-Reserve.d6350258.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 17 - Feb 18](https://www.expedia.com/Hotel-Search?regionId=6350258&startDate=2026-02-17&endDate=2026-02-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 18 - Feb 19](https://www.expedia.com/Hotel-Search?regionId=6350258&startDate=2026-02-18&endDate=2026-02-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=6350258&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6350258&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. 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(12 reviews) [](https://expedia.com/Santa-Cruz-Hotels-Equipetrol-Suites-Apart-Hotel.h90599395.Hotel-Information) ![Casa Por Temporadas](https://images.trvl-media.com/lodging/116000000/115110000/115103700/115103642/874f6beb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa Por Temporadas Barrio Las Pampitas, calle 3 Nro. 99 Santa Cruz Santa Cruz Department $86 nightly $86 total Feb 18 - Feb 19 10/10 Exceptional! (1 review) [](https://expedia.com/Santa-Cruz-Hotels-Casa-Por-Temporadas.h115103642.Hotel-Information) ![Amaca Hostal](https://images.trvl-media.com/lodging/109000000/108360000/108355000/108354969/c57afee2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Amaca Hostal 249 Independencia Santa Cruz Departamento de Santa Cruz [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F3%2F2026&endDate=3%2F4%2F2026&selected=108354969&PinnedHotelID=108354969&HadPinnedHotel=true®ionId=6350258) [](https://expedia.com/Santa-Cruz-Hotels-Amaca-Hostal.h108354969.Hotel-Information) ![Hotel Viru Viru II](https://images.trvl-media.com/lodging/45000000/44250000/44249400/44249394/79b8ea19_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Viru Viru II Av. 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